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Solid-phase extraction (SPE) is a separation process by which compounds that are dissolved or suspended in a liquid mixture are separated from other compounds in the mixture according to their physical and chemical properties. Analytical laboratories use solid phase extraction to concentrate and purify samples for analysis. Solid phase extraction can be used to isolate analytes of interest from a wide variety of matrices, including urine, blood, water, beverages, soil, and animal tissue.
SPE is solvent consumption, convenient, safe and hige efficiency. According the principle of "like dissolves like", SPE can be classified in four types: inverse SPE, normal phase SPE, ion exchange SPE, absotption SPE.
SPE column
